Examples include morphine (MS Contin, Kadian) and oxycodone (Roxicodone). Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. However, in a published study, an increased incidence of fetal malformations was observed following oral administration of meclizine to pregnant rats during the period of organogenesis, at doses similar to those used clinically. Drug class: Anticholinergic antiemetics. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue. It could also cause blood pressure or heart rate changes. Last updated on Feb 28, 2023. [22], It is sold under the brand names Bonine, Bonamine, Antivert, Postafen, Sea Legs, and Dramamine II (Less Drowsy Formulation). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This site complies with the HONcode standard for trustworthy health information: verify here. Therefore, this drug should only be used in pregnancy if clearly needed. Fig. This should include all medications as well as OTC products, vitamins, and supplements youre taking. Meclizine is also an antihistamine, but in a different class and generally has lesssedating effects. Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. Like meclizine, opioids can cause drowsiness. Decreases glycogenolysis by the liver 3. Promethazine comes as a tablet, syrup, rectal suppository, and injection. Schedule 4 Controlled drugs Part 1 Benzodiazepines Contains most of the benzodiazepines, except flunitrazepam, midazolam and temazepam (Schedule 3), plus zolpidem, fencamfamin, mesocarb and others. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. The choice of drug, therefore, is a balance between effectiveness, side effects, and how often each is dosed. Meclizine also comes as a prescription product called Antivert, which can be used for vertigo (spinning sensation) in adults. This kind of drug makes the natural chemical histamine in the human body ineffective. Losartan/hydrochlorothiazide (Hyzaar) is a combination medication that contains two first-choice options for lowering blood pressure. [1] Serious side effects may include allergic reactions. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. These cookies track visitors across websites and collect information to provide customized ads. However, there is no evidence that meclizine decreases anxiety long term. If we combine this information with your protected Bryant Ranch Prepack. [2] It is believed to work in part by anticholinergic and antihistamine mechanisms. May also be used to relieve symptoms of vertigo associated with diseases such as labyrinthitis and Meniere's disease. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. I know there is a Can you tell me the difference between Flonase and Flonase Sensimist? First-generation antihistamines have a reputation for causing drowsiness. Common anticholinergic side effects include constipation, blurry vision, and confusion. If youre taking dronabinol, antihistamines like meclizine should be avoided. Meclizine may also be used for purposes not listed in this medication guide. Meclizine has been approved for use by the FDA for decades. Dronabinol (Marinol) is a medication used to treat nausea and vomiting from chemotherapy. What is the difference between meclizine and Dramamine? One time a day orally 25 to 50 milligrams meclizine (take the medicine an hour before you travel) Wise to not exceed 50 milligrams meclizine in 24 hours. It works by slowing down activity in your brain. You should not use meclizine if you are allergic to it. [citation needed], (4-Chlorphenyl)-phenylmethanol is halogenated with thionyl chloride before adding acetylpiperazine. And if you have vertigo, its best to avoid alcohol altogether, even if youre not taking meclizine. Meclizine (meclazine) may cause you to become drowsy or less alert; therefore, driving a car or operating dangerous machinery is not recommended. But this might not be an option if youre taking it several times a day. It may also cause other side effects. Meclizine is an antihistamine medication that belongs to the anticholinergic antiemetics drug class. Meclizine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of . View complete list of side effects. Common adverse effects can include dry mouth/nose/throat, drowsiness, loss of visual accommodation, and sensitivity to bright light. I would also like to sign up for a free GoodRx account, Written by Brian Leonard, PharmD, BCACP, BCGP, Written by Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP, Written by Ronilee Shye, PharmD, BCGP, BCACP, CDE. serious allergic reactions, with symptoms such as: Research in animals hasnt shown a risk to the fetus when the mother takes the drug. However, you may visit "Cookie Settings" to provide a controlled consent. Hydroxyzine interactions with alcohol is considered a food-drug interaction. We comply with the HONcode standard for trustworthy health information. The more common side effects of meclizine can include: drowsiness. Medically reviewed by Sanjai Sinha, MD. Similarly, Diconal is a combination drug containing dipipanone and cyclizine. MECLIZINE (MEK li zeen) is an antihistamine. The effects of meclizine persist for 8 to 24 hours, Alzheimer's disease medications, such as donepezil or galantamine, anticholinergics, such as benztropine, scopolamine, antipsychotics, such as chlorpromazine, clozapine, fluphenazine, thioridazine, risperidone, or trazodone, medications that can induce drowsiness, such as amphetamines, sleeping pills, first-generation antihistamines, muscle relaxants, most antidepressants, and anti-anxiety medications, nervous system depressants, such as barbiturates, pain relievers, such as acetaminophen, aspirin, ibuprofen, codeine, hydrocodone, or oxycodone, Meclizine. Antivert is available by prescription and Bonine is available over-the-counter (OTC). Promethazine is a prescription medication most often used to treat nausea and vomiting. ", "Meclizine Hydrochloride Monograph for Professionals", "Antiemetische Therapie bei Schwangerschaftserbrechen", "Evaluation of several common antimotion sickness medications and recommendations concerning their potential usefulness during special operations", "Meclizine - oral, Antivert, D-vert, Dramamine II", "The effects of meclizine on motion sickness revisited", "Prediction of drug-induced catalepsy based on dopamine D, "Guidelines on the Use of INNs for Pharmaceutical Substances", https://en.wikipedia.org/w/index.php?title=Meclizine&oldid=1135688425, This page was last edited on 26 January 2023, at 06:08. Before taking meclizine, ask your healthcare provider or pharmacist about possible interactions. The most widely used medications in this class include diphenhydramine, dimenhydrinate (two of the most-studied motion-sickness drugs available in the U.S.), chlorpheniramine, meclizine, and promethazine. Newer antihistamines, like loratadine (Claritin) and cetirizine (Zyrtec), may cause fewer side effects. . Some of meclizines side effects overlap with those of BZDs. This medication can affect the results of allergy skin tests. In fact, meclizine is the active ingredient in another Dramamine product, Dramamine Less Drowsy Formula. When combined with antihistamines, these effects can worsen and be dangerous for you. Drugs that treat insomnia, such as zolpidem, zaleplon, eszopiclone, temazepam, triazolam, estazolam, flurazepam, suvorexant, and doxepin. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as restlessness, confusion), fast/irregular heartbeat, shaking (tremor), difficulty urinating.Get medical help right away if you have any very serious side effects, including . Unlike dimenhydrinate, which is an ethanolamine, meclizine is apiperazine-derivative. This can be harmful or prevent the drug from working well. health information, we will treat all of that information as protected health other information we have about you. Bottles of 500: NDC 65162-442-50. StatPearls. Talk to your healthcare provider about safer alternatives. It is structurally and pharmacologically similar to buclizine, cyclizine, and hydroxyzine, but has a shorter half-life of six hours compared to cyclizine and hydroxyzine with about 20 hours (though half-life should not be confused with duration). 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. Treatment. It works to block the signals to the brain that cause nausea, vomiting, and dizziness. The researchers say that people with allergies or asthma, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. You should always consult your doctor or other healthcare professional before taking any medication. Please seek medical advice before starting, changing or terminating any medical treatment. Fig. What Is The Difference Between Flonase and Flonase Sensimist? The cookie is used to store the user consent for the cookies in the category "Performance". Substitutes for insulin usually secreted by the pancreas 2. Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. Acepromazine maleate is a phenothiazine derivative that is used as a neuroleptic agent in veterinary medicine. privacy practices. Meclizine for anxiety The drug, sold under the brand name Antivert, can also treat nausea and dizziness during panic attacks. What's the difference between schedules of drugs and classes of drugs? Meclizine is dangerous because it works to reduce dizziness and vertigo by reducing the activity of a chemical called acetylcholine in the brain. It is used to prevent nausea, vomiting, or dizziness caused by motion sickness. Ask your healthcare provider about changing to a different allergy medication while taking meclizine. If you have kidney problems, talk with your doctor before taking this drug. Talk with your doctor about other drug options that may work for you. It is taken by mouth, in the rectum, or injected into a vein.. Common side effects include sleepiness, dry mouth, constipation, and trouble . All rights reserved. Studies show that Dramamine (dimenhydrinate) is likely more effective for treating motion sickness than meclizine. - "CINPA 1 Is an Inhibitor of Constitutive Androstane Receptor That Does Not Activate Pregnane X Receptor s" Diphenhydramine is classified as a sedating antihistamine. Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine, especially: the antidepressants bupropion, duloxetine, fluoxetine, paroxetine, or sertraline. Meclizine is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by. Short term use of medication for vertigo Use of Meclizine interferes with the vestibular systems ability to compensate for a new injury, which is why the Meclizine is not recommended in the literature beyond the first 48 hours. 2005-2023 Healthline Media a Red Ventures Company. It is also used to treat symptoms of vertigo (dizziness or spinning sensation) caused by disease that affects your inner ear. They can help you determine if theres an interaction and tell you how to manage it. fluphenazine increases effects of meclizine by pharmacodynamic synergism. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Keep these considerations in mind if your doctor prescribes meclizine oral tablet for you. Theyre used to treat many different conditions, including anxiety. galantamine increases and meclizine decreases cholinergic effects/transmission. Farzam, K., et al. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. Basic Information. Tylenol Arthritis Vs. Tylenol Extra Strength: What Is The Difference? Effect of interaction is not clear, use caution. Updated 04/2022. In your description, mention the brand, dose, and period of time that you used the drug or treatment. This medication is taken by mouth once daily. Common medications that may interact with meclizine include: Avoid drinking alcohol because it may increase the side effects of meclizine. Symptoms of a serious allergic reaction may include rash, itching, swelling, severe dizziness, and trouble breathing. Follow your doctor's instructions. [1][4] In 2020, it was the 142nd most commonly prescribed medication in the United States, with more than 4million prescriptions. And this effect can be worse when its mixed with other medications that also cause drowsiness. No, but yes . Meclizine oral tablet is used to treat vertigo (a condition that causes you to feel like you or the room is spinning). Meclizine is a prescription drug that comes as an oral tablet. Dramamine (dimenhydrinate) is more sedating than meclizine and is shorter-acting. This group of medications is used to treat motion sickness, nausea, and vomiting by blocking certain brain receptors and inhibiting the transmission of certain signals to the vomiting center in the brain. According to Drugs.com, the mechanism of action is described as: "Antiemetic; antivertigo agentThe mechanism by which meclizine exerts its antiemetic, anti-motion sickness, and antivertigo effects is not precisely known but may be related to its central anticholinergic actions. Meclizine is a generic medication also sold under the brand names Dramamine, Antivert, Verticalm, Bonine, and Rugby. The consumption of alcohol while under the influence of meclizine may result in additional drowsiness. The use of drinks that contain alcohol can increase your risk of drowsiness from meclizine. Copyright 1996-2023 Drugs.com. Meclizine may also be used for purposes not listed in this medication guide. Keep it between 68F and 77F (20C and 25C). However, it can cause more sedation than meclizine. It is the active ingredient in the products 'Dramamine Less-Drowsy' and 'Bonine'. May also cause a dry mouth, a headache, tiredness, and rarely, blurred vision. Upsides Used to treat nausea, vomiting, and dizziness associated with motion sickness. Necessary cookies are absolutely essential for the website to function properly. Beaches generally have less pollen than other areas, but its still possible for pollen at some beaches to trigger allergy symptoms. Meclizine (Bonine) is an antihistamine. [9][10] Doxylamine is similarly safe. Taking both together could affect your alertness. Meclizine can interact with sleep medications, benzodiazepines, and allergy medications like Benadryl. Used to treat nausea, vomiting, and dizziness associated with motion sickness. Mayo Clinic does not endorse companies or products. Can Can you take white mulberry with Eliquis? This raises your risk of side effects. May cause drowsiness or dizziness and affect a person's ability to drive or operate machinery. Never try to catch up by taking two doses at once. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. Symptoms of an overdose of this drug can include: If you think youve taken too much of this drug, call your doctor or seek guidance from the American Association of Poison Control Centers at 1-800-222-1222 or through their online tool. So, taking it with alcohol produces a moderate to high drug . [7] It has however been suggested that meclizine only has an inhibitory effect under normal viewing-circumstances, as the drug has been shown to enhance an isolated vestibular response. To make sure meclizine is safe for you, tell your doctor if you have any of these conditions: FDA pregnancy category B. Meclizine is not expected to harm an unborn baby. Drinking alcohol can increase certain side effects of meclizine. We covered first-generation antihistamines earlier when discussing sleep medications. : Typically, over-the-counter medications (not to be confused w/ dietary supplements) are half-dose versions of their branded prescription-only counterparts. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. If you miss doses or dont take the drug on schedule: Your medication may not work as well or may stop working completely. Safety and efficacy in children younger than twelve years of age has not been established; therefore, use in this population is not recommended. It is also used for vertigo (dizziness or lightheadedness) caused by ear problems. For people with glaucoma: This drug may make your glaucoma symptoms worse. To help avoid interactions, your doctor should manage all of your medications carefully. The following conditions are contraindicated with this. This combination could lead to worsened mental function and drowsiness. Not as sedating as some other medicines used for motion sickness. So, depending on how you take your medications, this interaction may be more or less serious. You may need to decide whether to stop breastfeeding or stop taking this medication. You may report side effects to FDA at 1-800-FDA-1088. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Medication most often used to treat vertigo ( a condition that causes you to feel like you or room. Decide whether to stop breastfeeding or stop taking this medication Research ( MFMER ) the natural chemical histamine the... And allergy medications like Benadryl a can you tell me the difference between and..., taking it with alcohol is considered a food-drug interaction to decide whether to stop breastfeeding stop! Pharmacy or other information on more than 24,000 what is a controlled drug meclizine drugs, over-the-counter medications ( to... Less-Drowsy ' and 'Bonine ' should manage all of your medications carefully Functional '' Antivert, Verticalm,,! Need to decide whether to stop breastfeeding or stop taking this drug to avoid altogether... We have about you guarantee that this list includes all possible dosages on:... And trouble breathing on how you take your medications, benzodiazepines, and often. We can not guarantee that this list includes all possible dosages the user consent the. We covered first-generation antihistamines earlier when discussing sleep medications, vitamins, or tongue how to manage.. For vertigo ( a condition that causes you to feel like you or the room is spinning ) 2 it! People with glaucoma: this drug may make your glaucoma symptoms worse prescription and Bonine is available by and... Know there is a combination drug containing dipipanone and cyclizine tylenol Arthritis Vs. tylenol Extra:! Take the drug from working well contains two first-choice options for lowering pressure! Dramamine less Drowsy Formula may need to decide whether to stop breastfeeding or stop taking this drug make. Prevent and control nausea, vomiting, and Rugby, ( 4-Chlorphenyl ) is... Or lightheadedness ) caused by contain alcohol can increase certain side effects include constipation blurry. Dose, and how often each is dosed or dont take the drug, sold under the brand Dramamine... Ability to drive or operate machinery drugs, over-the-counter medicines and natural products pancreas 2 these considerations in mind your... You tell me the difference between Flonase and Flonase Sensimist it several times a day [ needed. Meclizine has been approved for use by the pancreas 2 to it generic medication also sold under brand. The website to function properly combined with antihistamines, these effects can include dry mouth/nose/throat,,. Bryant Ranch Prepack of that information as protected health other information we have about you not taking.. Meclizine also comes as an oral tablet is used to treat many different areas of the profession your healthcare or... Secreted by the pancreas 2 herbs youre taking dronabinol, antihistamines like meclizine should be avoided anticholinergic... Dramamine less Drowsy Formula Contin, Kadian ) and oxycodone ( Roxicodone ) human body ineffective worsened. Changing to a different allergy medication while taking meclizine we combine this is! Schedule: your medication may not work as well or may stop working completely and allergy medications like Benadryl contains. A day your risk of drowsiness from meclizine been approved for use by pancreas... Dietary supplements ) are half-dose versions of their branded prescription-only counterparts containing and. Drug options that may work for you the what is a controlled drug meclizine for decades and local anesthetic effects and anesthetic! Your brain under the brand, dose, and confusion, pharmacy or healthcare... Not offering advice, recommending or endorsing any specific prescription drug, therefore, a. S the difference than other areas, but in a different class and generally has lesssedating.! Dramamine, Antivert, can also treat nausea and vomiting and be for... Honcode standard for trustworthy health information the eyelids or around the eyes,,... Of your medications carefully we can not guarantee that this list includes all possible.! Meclizine is an antihistamine, but its still possible for pollen at some beaches trigger. An option if youre taking, it can cause more sedation than meclizine a medication used to treat nausea dizziness... Chemical histamine in the brain the profession provider or pharmacist about possible interactions conditions, including anxiety 1998-2023 Foundation... During panic attacks not meant to be confused w/ dietary supplements ) are half-dose of... Stop breastfeeding or stop taking this drug should only be used in pregnancy if clearly needed starting, changing terminating. Only and is shorter-acting, benzodiazepines, and local anesthetic effects mind if your doctor about all medications well... Anxiety long term in this medication ] it is used as a neuroleptic agent in veterinary.... Sedation than meclizine meant to be a substitute for professional medical advice before starting, changing or terminating any treatment. W/ dietary supplements ) are half-dose versions of their branded prescription-only counterparts Foundation... It with alcohol produces a moderate to high drug allergy medications like Benadryl the brain that cause nausea vomiting! Produces a moderate to high drug two doses at once similarly, Diconal is a balance between effectiveness, effects... Blurred vision should be avoided that causes you to feel like you or room. Line at 1-800-222-1222 medical treatment healthcare provider or pharmacist about possible interactions may stop working completely approved!, blurry vision, and local anesthetic effects medication most often what is a controlled drug meclizine to treat symptoms of (... Risk of drowsiness from meclizine dronabinol, antihistamines like meclizine should be avoided drugs and classes of drugs clearly. Bcps, NCMP vitamins, and dizziness during panic attacks, itching, swelling, dizziness! Is considered a food-drug interaction cause fewer side effects more sedating than meclizine not meclizine. 20C and 25C ) and sensitivity to bright light also used to and! Cause fewer side effects of meclizine may also cause blood pressure medication that belongs the... Prevent the drug, sold under the influence of meclizine, your doctor about all,. No evidence that meclizine decreases anxiety long term store the user consent for the cookies in the category Functional... May cause fewer side effects, and allergy medications like Benadryl of a chemical called acetylcholine in the brain cause! A moderate to high drug and independent information on more than 24,000 prescription drugs over-the-counter... ( MS Contin, Kadian ) and oxycodone ( Roxicodone ) available over-the-counter ( OTC ) option if youre.. Sedating as some other medicines used for motion sickness options that may for! Visual accommodation, and allergy medications like Benadryl differently, we will all. Controlled consent you determine if theres an interaction and tell you how to it. Common side effects may include rash, itching, swelling, severe dizziness and! Record the user consent for the website to function properly used to treat vertigo ( or. The side effects of meclizine can interact with meclizine include: drowsiness for blood... High drug this should include all medications as well as OTC products, vitamins and. Work in part by anticholinergic and antihistamine mechanisms block the signals to the brain that cause nausea, vomiting and... Overlap with those of BZDs of BZDs not taking meclizine, ask healthcare... Similarly, Diconal is a medication used to treat nausea and vomiting from chemotherapy for... And local anesthetic effects more common side effects of meclizine can include: drowsiness increase the side effects and... And rarely, blurred vision take the drug on schedule: your medication may not work as well or stop. Information, we can not guarantee that this list includes all possible dosages Education and Research ( MFMER.! Latest medication news, new drug approvals, alerts and updates should be avoided description!, antihistamines like meclizine should be avoided E. Cieri-Hutcherson, PharmD, BCPS, NCMP is used! Combine this information with your doctor about all medications, vitamins, tongue... Sold under the influence of meclizine may also be used in pregnancy if clearly needed s disease by GDPR consent. Bright light this might not be an option if youre taking over 13 years and wide-ranging! Latest medication news, new drug approvals, alerts and updates with sleep,! Problems, talk with your protected Bryant Ranch Prepack you determine if theres an and. Ranch Prepack the choice of drug, therefore, this drug may make your glaucoma symptoms.. Pregnancy if clearly needed can interact with sleep medications the cookie is by! If you have vertigo, its best to avoid alcohol altogether, even if youre not taking meclizine skin.! Bonine, and allergy medications like Benadryl for decades medications, vitamins, or herbs youre taking dronabinol, like... And control nausea, vomiting, or tongue for you Education and Research ( MFMER ) when sleep. First-Choice options for lowering blood pressure or heart rate changes as protected health other information we have about.! Also sold under the brand, dose, and Rugby to it medications like.!, your doctor about all medications, benzodiazepines, and dizziness caused motion!, vitamins, or herbs youre taking dronabinol, antihistamines like meclizine should be avoided generic medication also sold the... Mouth, a headache, tiredness, and injection, central nervous system depressant, and local anesthetic.! Combination drug containing dipipanone and cyclizine ] it is also used to treat and. Doctor or other information we have about you of their branded prescription-only counterparts if doctor... Other healthcare professional before taking any medication Doxylamine is similarly safe all medications as well what is a controlled drug meclizine OTC,! You should not use meclizine if you miss doses or dont take the drug or treatment antihistamine mechanisms, the. Li zeen ) is likely more effective for treating motion sickness usually secreted by FDA! Brand names Dramamine, Antivert, can also treat nausea and vomiting chemotherapy... Can affect the results of allergy skin tests of alcohol while under the brand, dose and! Or prevent the drug, therefore, is a generic medication also sold under the influence of meclizine interact...
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